Philosophically, instead of treating after ill, better not let to be infected in advance! For instance, it is advantageous not to be infected by corona (if possible) than to have a treatment (if any at all). However, in reality this is not easy to accomplish, in particular if this corona is not only invisible, but also it is transmitted mainly through air droplet! Moreover, it becomes hard to be safe, if the pandemic induce a socio-economical and even political temperature. For instance, if the accountable bodies deliberately are involving in adverting for non-feasible intramuscular mode of vaccines for such pathogen, as a result which in this century, when civilization is trying to conquer the universe, we can’t stop when SARS-CoV-2 is crumbling lives as an autumn leaves. Therefore, the question “how not to contract the disease COVID-19”? – is a tangible question to get a real answer at this day. As a biochemist, we tried to alert the world; about what we are thinking is better. Moreover, published 6 manuscripts on the issue. Nevertheless, still no effective measures from responsible international organizations like WHO. Now, what we decided is to address a separate work on the principle of “stay at safe place and or never wear off Face Mask until return back”. For this, we implemented a survey (primary data collection) and clinical-epidemiology based secondary data analysis. As a result, which, not only we approved our hypothesis about a stay safe mandate, with methodologies on how to realize such campaign, but also in the global health system we revealed many odds, among which – WHO do not have a common way of registering-analyzing respiratory based infectious diseases and of course we exposed an atypical fact that in this globalization world not all nations are enclosed under this organization.

1.1 Philosophical backgrounds
Who and how can answer for the following an attitude based two questions?
What is better - not to let somebody to perform criminal or first permit him, then punish for his illegality latter? And
How is better – aggressively and bitterly but radically to solve a problem or take prolonged and weak measures, because of which will be forced to live extra time (if there can be an end at all!) with the dilemma?
1.1.1 Certainly, it is better to prohibit him from doing something wrong in advance. This means that if you forbid somebody to perform something illegal or if you can abolish the illicit-junk element itself, then there will not be him (the illegal) too. If we solve the first question in this manner, then no need to think over, how to respond to the second issue.

1.1.2 The same philosophy can be applied for pathogenic infections: Instead of treating (after ill), better not let to be infected! For instance, it is advantageous not to be infected by corona (if possible) than to have a treatment (if any at all). Anyway, “how not to have the infection”? – This is a tangible question to get a real answer

 1.2 statement of the problem
Neglecting, their socio-economic and political impacts, COVID-19 and others respiratory tracts-based diseases (RTID) are taking millions lives each year [1,2,3,4,5]. To our part, through the Twitter-Facebook’s social pages and in all our published manuscripts [4-9], we have been trying to apprise for the world about the easiest, cheap and short cut options that can effectively help us to stop RTIDs. Now too, through this the 7th our RTID related study, we are going to suggest a simple solution - not letting the coronavirus and others RTID causing pathogens to enter into our respiratory tracts.

This idea was begin on March 9, 2020 during our speech to the University’s COVID-19 task force. In that meeting, we were have had offered to produce 10000 Face Masks within the university level. Latter, when the Ethiopian media announced as if for such virus discovered a traditional drug and moreover, after the officials tried to washout the city’s road with antiseptic like fluid; and when international bodies, in particular the WHO started distorting the scientific principle of RTID, we begin to twit and emailing to WHO about all its odds. Additionally, to the Ethiopian governmental officials, we prepared a 28 pages proposal [9]. In it, again we tried to alert about the vitality of Face Mask. Moreover, except in social media, in our first published work [4], among the 5 possible control-prevention measures, the priority goes to prophylaxis options (based on the nature of its host cells, we excluding the vaccination). In it, we enclosed the Face Mask.

1.2.1 How possible not to to let the corona and others pathogens to infect us?
To be free from such pathogens, every assumption leads to the main options – to the two “DO NOTs”:
1.2.1.1 Do not contact (pass across) with the pathogen: don’t be there, where it is ought to be. For instance, avoid it by forbidding the infected to be around you. or
1.2.1.2 Do not let the pathogen to be around you (use effective defense mechanism)
Certainly, since, both directions are practicable, it is not easy to prioritize either. Particularly, if raises individuals’ right issue! Nevertheless, for us, the second option (1.2.1.2) - not to let the COVID-19’s virus – SARS-CoV-2 pathogen to be present around the possible victim is more attractive. Hence, if corona is absent, or if we can organize a self-fencing against it, then no snag at all. However,
1.2.2 To evaluate this half rational postulation, there are four theorems-arguments:
1.2.2.1 Do not let the coronavirus to be nearby - it is impossible, because already we have it;
1.2.2.2 Do not let the potential victim to come closer to it – impossible, because it is not visible, but contagious, mainly via atmospheric content – the air that we breathe;
1.2.2.3 Ignore it, because, after the death of those that are vulnerable to it or after many of us adopt a hard immunity (through local immune system [7]) the virus will disappear (may not have a host to continue reproducing); or
1.2.2.4 Intercept (shut) the path through which the pathogen can be transmitted/infects the host. This can be rephrased as - protect (shed-cover) the potential victim from being exposed to the virus.
Well, if we relate the 1.2.2.4 as a derivation from 1.2.1.2, then again the question “but, how?” is more than substantial. Therefore, if we can able to answer it properly, we can achieve a game changer result in fighting with such pathogen.
1.3 hypothesis
1.3.1 According to the above theorems (1.1.2 and 1.2.2.4), more preferable answer for our postulation is - not to let the virus to enter into our respiratory tracts [5,6,8]. In particular, by partially covering-closing the three openings-cavities: the two nostrils’ and oral’s cavities
1.3.2 Certainly, since the virus enter into our respiratory tracts through nostrils’ and oral cavities, covering/sheltering these cavities from contacting with the virus is the decisive measure and serves as our hypothesis “effective-feasible measure to stop the COVID-19’s pandemic”: are stay at safe place (SaSP) and if forced to go out never wear off Face Mask (NOFF) until return back. As seen in the twit 1, since April 2021, this hypothesis has been conceived and grown in our mind, as a result which we tried to enclose it into the 6th our published manuscript [8]. However, not to make the manuscript bulky (it contains 3 separate articles (information)) and to have more attention by publishing it separately, we launched this 7th study that focuses only on SaSP and NOFF. Earlier, we tried to give a clue for stakeholders by publishing manuscripts [4,5]. For instance, the following pie chart 2, was designed on April 2020 naming as - ‘the secret of success against COVID-19’ (refer to pie chart 1):

1.3.3 In other words: ‘How and for what duration should our three cavities be covered during a SaSP campaign?”: - For the question ‘how?’ – being far away from the possible place (location), where the virus may circulate or cover your cavities until you will be there, where shouldn’t be the virus. For the second question ‘for how long?’, although, to firmly hypothesize we are not epidemiologist, so, hope, we will found hints during this study.

1.4 Aim of the study
We launched this 7th study to justify the vigorous roles of SaSP and NOFF to stop RTIDs pandemics, because, in additional to the content mentioned above (1.2):
1.4.1 To re alert world that no stakeholder, even our university doesn’t consider our earlier works [5,6,8,9], in which we have postulated the easiest, fastest, and cheapest, but feasible-effective measures to stop not only the current pandemic (refer to our twit from April 3, 2021), but also to minimize (if not abolish) others airborne/air droplet respiratory based pathogens is the SaSP and NOFF mandates. Not only through publication, but also using own Face Book-Twitter pages, tried to alert the globe about Face Mask’s advantages, deliberately (at least due to pharm business); lack of understanding the nature of COVID-19; and lack of awareness about the exceptionality of human respirator’s tissue, the accountable bodies do not properly-firmly aware their nations about this vital safeguard (Face Mask) against respiratory based pathogens! As a result, which in this 21st century, when civilization is trying to conquer the universe, this pandemic is crumbling lives as an autumn leaves;
1.4.2 Today’s science-based articles are oriented only for specialists; because of which public cannot easily retrieve actual information. Therefore, to publish public oriented article; and
1.4.3 To reveal the vitality of SaSP and NOFF, through publishing a separate article about their nature-characteristics and role. Although, we are poor in epidemiology-oriented study, will implement a survey (primary data) and epidemiology based secondary data analysis, to:
1.4.3.1 indirectly justify the hypothesis (1.3) that because of Face Masking, comparing to the past 3-5 years (2019 and before it – using them as a control), influenza and lung tuberculosis (TB) like RTIDs decreased during the pandemic’s years;
1.4.3.2 We will try to forecast when and how long to implement the SaSP-NOFF mandates campaign, to stop not only this pandemic, but also at least to minimize others RTID like: flu-influenza and lung TB.

 2.1 Assessing public’s knowledge, attitude, and practice on the Face Mask’s rol
2.2 Comparing the burden of RTID before (at least 5 years data on prevalence) and during the 2020 and 2021 2.3            Reviewing Face Mask related literatures
2.4 Determining how long is possible the “SaSP and or NOFF” campaign

Based on the stated objectives, the research design [10,11] will have three main directions (refer to chart 2 below):

3.1. Field survey (Primary data): Observing-recording, discussion-interview on Face Mask related issues
3.1.1. Recording (picturing) on the street and indoor events - a primary data.
To evaluate how far is accurate the public’s awareness on Face Mask usage, we will analyze what we have observed (during pandemic’s two years) on the streets and indoor events (meetings conferences, etc.)
Tools: audio-video recorder camera and internet as well.

3.1.2. The discussion and interview part will focus on both the public and health workers respectively.
Tools: we are going to implement three questions (in Amharic language):

    3.1.2.1  ??????????????????3 ???????????????????????????????????????????????????????????????????????????????

Its translation into English: ‘earlier, before the corona emerged, at least three times/year was infected by influenza like RTID, but now “It is almost two years passed since I have no influenza like illness. Why, I am not infected for so much long time?”

 3.1.2.2 Incase, if a respondent’s answer for the above question will included not “face mask”, then followed the second question in Amharic: - ?????????????????

    In English may be – ‘what can you say about face masking?’
3.1.2.3 ?????????????????????????????????????????????????30 ???????????????????????? ????
Its English version may have the following sense: What do you think, can influenza, TB, COVID-19 and others infections that are transmitted through air droplets/air borne will be disappeared if the whole world agrees to stay at home for 30 days? Why?

3.2 Clinical - epidemiology based secondary data collection
Burden-incidence of influenza, TB, etc., like RTID during the 5-7 years (as controls) and during the 2020 and 2021 (experimental data)
3.2.1 prevalence (burden) of influenza like RTID within Ethiopia
3.2.2 In others geographical regions: North hemisphere (Canada, USA, and UK, South Korea); tropical (Argentina, Kenya, Australia); and Southern hemisphere (South Africa)
3.2.2.1 Secondary data on prevalence of RTID will be collected from the following sources: Addis Ababa health centers; city’s health office bureau; and ministry of health (its data will represent the whole country’s burden)
Except Ethiopia, others countries from which we are going to take sample data of the prevalence of influenza like RTID should be 3-5 countries, that are located in 3 different hemispheres (north, south and tropic)

As seen in the table 1, there are possible different types of RTID (but not limited to), from which we will take 1 or 2 for comparing the control (2019 and earlier 5-10 years) and pandemic’s years’ (2020 and 2021) burden
3.3 Literature based secondary data on control-prevention measures against influenza, TB, COVID-19 RTIDs.
The literature-based data will target more often the Face Mask within the campaign of NOFF
3.3.1 The sanitation-hygiene, distancing and vaccination are said to be prophylaxis measures. However, for this work our focus is the Face Mask as the representative for NOFF. Therefore, during literature review, we are going to focus by dividing the data that we are going to collect at least into 4: 3.3.1.1 History-Development of the Face Mask; 3.3.1.2 Characteristics of Face Mask; 3.3.1.3 Types of Face Mask; 3.3.2.4 Structure of Face Mask; 3.3.1.5 Utilization of Face Mask
3.3.2 Draw backs of Face Mask
3.4 lock down
3.4.1 history of lockdown; 3.4.2 lock down during COVID-19 pandemic; 3.4.3 draw backs of lockdown measures
3.5 How to implement the SaSP and NOFF
3.5.1 How long lasts COVID-19 infection; 3.5.2 how long the infected can be active to infect others

4. Results of primary data (the survey); secondary data analysis and literature review
Based on line chart (refer to methodology), we arranged this research’s result into: field survey - picturing-recording activity to assess on how public uses Face Mask and discussion-interview during these pandemic years (primary data); secondary data collection (on the prevalence of RTID in Ethiopia and others three geographically in different locations); review literature on nature and role of Face Mask lockdown mandate (which may highlight for how long to use SaSP and NOFF for 30 days to stop wave of COVID-19 and others RTID as well.

Based on givens in [3,5,6,13,14], Influenza viruses and others like TB, COVID-19, etc. RTIDs’ pathogens are easily transmitted, predominantly via the droplet/aerosol; contact routes; and by indirect spread from respiratory secretions on hands, tissues, fomites, etc., (if enter through nostrils’ and oral’s cavities). Therefore, we started to study the public how it tries to defend from coronavirus through covering mouth and nostrils. Therefore, about one of the option - the Face Mask that prevents illness from RTIDs, we surveyed as follows:
4.1  Field survey (primary data): Observing and picturing to evaluate public’s awareness on Face Mask’s utilization.
4.1.1 Observing and recording (picturing) on the street and indoor events - a primary data
To evaluate how far the public uses Face Mask within the last two pandemic’s years (2020 and 2021), periodically we recorded-pictured on the street the public’s behavior - (how far public takes the distance keeping and Face Masking prophylaxis options). However, for convenience (not to make the manuscript bulky and to pay less publication fee), we selected pictures of only 3 intervals of the years (April, August, November-December) of both 2020 and 2021).

4.1.1.1 Observing and recording (picturing) in Addis Ababa (Ethiopia).
As a tool we used mobile for audio-video records

04.2021 all masked for bus from 7 of us 2 didn’t wear mask 11.2021 they only carry mask
The above 6 photos have been selected from April, August, and November-December pandemic’s years collections.

As seen in the first column, during holydays (04.2020), almost no one is masking. Around August 2020 the mandate of masking started being applied strongly (8.21 90% wearing at bus station queue): Without mask, no right to enter into the public transport. Moreover, as seen in the 2nd column, the man has a scarf (maybe he thinks that it can be an additional protector). At the end of 2020 too, around bus station, most people use Face Mask. When we come to the year 2021, at its end (November 2021), there is a relaxation tendency - as seen in the 3rd column the youths not wearing, rather carry their masks, since no policemen around. Even, as seen in the last column of table 6, the present of one of the greatest country – do not wear Face Mask during indoor meeting.

4.1.1.2 Others countries public’s relation to Face Mask
What was the the situation in other countries? There, comparatively the situation is worsening. As seen in both of the two pandemic’s years against lock dawn, Face Mask and vaccination mandate rises (refer to table 4). Moreover, [15] wrote that COVID-19 Is fueling Unrest in the US in demonstrations. In demonstration-protest, the public is said to be without Face Mask.

In the tables 4, 5, there are 3+3 selected (by quarterly) photos from 2020 and 2021 collection: almost in all pictures the Face Mask mandate is not obeyed by protesters – demonstrators. Even soldiers didn’t wear Face Mask.

4.1.1.3 Indoor events and Face Mask in Ethiopia
The other type of our survey study was observing and recording indoor events: Participants, that more or less are from educated part of a society, do not follow the Face Mask mandate. It is accustomed to drink in such crowded halls. Moreover, on the issue, we ourselves have had a conflict within own university’s officials;

4.1.1.4 Indoor events and Face Mask in other countries
In indoors, there is less surface and air movement. Therefore, probability to be infected in such place is high. Nevertheless, in hotels and others events speakers even do not Face Masking.

Participants of conferences, financial annual economic forum in Davos and as seen in the last column of the table 4 even the president of USA do not wear Face Mask during indoor events
4.1.1.5 Posters and Ads: pictures from posters (instruction) against COVID-19 issues, at Addis Ababa (Ethiopia)
Posters are engines for any businesses, for which they are intended to give information about. Therefore, regarding to COVID-19 too, as a prophylaxis option, posters can play vital role in making awareness among the public [4]. However, their details should be approved by specialists.
See what kind posters are running: as seen in the following selected (table 7) they are harmful rather than giving positive impacts in fighting against the pandemic.

In the above group of pictures, the first was taken from a pharmacy’s entrance door in 2020. It alerts that hand shaking can transmit the virus. We pictured the middle poster from a bus station; in it there are 6 measures to be taken: wash your hand, do not go in crowded location, be at least 2 meters away from those who are sneezing, don’t hand shake, don’t touch your face-eyes-mouth unless you have a clean hand, and don’t eat raw meat products. However, in this poster there is nothing about Face Mask. The third poster (in 3rd column) is placed directly on Health Minister’s office floor. In it Face Mask is at the last line after “distancing, washing, and staying”. In [3] shows that the WHO on April 4, 2020 (after a day that we emailed to it) instruct an interim guideline from the WHO stated that healthy people did not need to wear masks because there was no evidence that masks can protect the wearers

4.1.1.6 social media on COVID-19 issues and Face Mask
Here under, regarding to prophylaxis measures, illustrated posters that have been prepared and twitted by WHO

In [16] too, inform us that WHO not only in its twitter page, but also as an article it has been spreading issues like a primary measure against COVID-19 is keeping distance.

Adopted and modified from twitter pages of MSM Monitor and WHO and may be Yahoo News

Collection of our twits 4: Sample of our twits within March and April 2020. As seen, we responded to WHO as follows: On April 30 (after WHO’s misinformation on prophylaxis principles), we twitted that the anti Ebola remdesivir has nothing to do with corona virus. In general speaking, our picture 1 and [4]- the first steps to be performed if a disaster erupt. As seen in twit 4, in March 31 we twitted about our emailing to WHO. On April 3, we have twitted that there are 7-9 errors in using the control-prevention prophylaxis measures. On April 30, 2020, we expressed our concern on how Media is broadcasting that Mr. Trump’s fellow informed as if a new finding that protein of the virus coat can be destroyed by sunlight (we afraid that such personnel do not pass-through high school biology of processing). We, our selves was set an experiment on March 9 2020 to determine the maximum temperature of hot water that human hands withstand (we were studying to use hot water together or without soap for sanitation issue in mass gatherings like University dining hall, in prison, sport academia, etc [5].

In twit 1, picture 3 and in this table 8 collection of twits, we ourselves are wearing Face Mask to be a model for surroundings. Even, when we send abstract for a conference [16], in the form we have had attached the photo with Face Mask. Moreover, although, the editor asked us to have photo without Face Mask, we refused, because of which the published work our name is without photo! In the table above, the first photo (in it about the vitality of Face Mask) although many works do not give attention about indoor events, the written (caption) in 3 languages indicate that even in such distance, if there is a wind, better not to wear off Face Mask: The 2nd and 3rd photos were taken in indoor toasting and in a graduation ceremony, respectively. However, to eat or to be picturing we do not take off the Face Mask, since the distance is not safe from being infected by air droplet/born pathogens like corona.

Certainly, as soon as we understand that the virus is somewhat the same as SARS-CoV, although the WHO itself on April 6, 2020 annonced as if no need to use Face Mask [3], we switched to Face Mask usage options [9]. So, we started on April, 2020, and further (after publishing 5 COVID-19 related works, as seen in the twit 1, our 30 days based hypothesis begin almost 18 months ago (we posted it on April 3, 2021 and August 13, 2021).

4.1.2 Discussion and interview on Face Mask issues
The discussion-interview part was held with the public and health workers respectively:
Tools: as an instrument (tool), we used the above mentioned (3.1.3.1 and 3.1.3.2) two questions
To our observation, starting in the middle of 2020 and ending at the middle of 2021 (4.1.2) at least in the public transport, everyone was using Face Mask. However, today at the end of November 2021, we have recorded a video on the crowded street. Within 3.1 minutes, from first 100 that we fixed 63% were wearing Face Mask!

4.1.2.1 Result of the discussion on the Addis Ababa streets
For the first our question-based discussion (refer to point 3.1.2.1 and 3.1.2.2): Why, almost for a year and half, I have no flu, what is the reason behind? And why we must use face mask?
From the first 100 respondents (random method [17,18]) on the street (from April – November 2021), 15 respondents wishes me not to be infected further (connecting with God’s willing); 17 answer – they do not know, with expression of non-willingness to have a conversation with me; 9 answered, because of face mask; 21, raised the hand washing issue; distancing raised by 6; 8 touched immunity issues; and 13 directly said that they do not want to deal with me on the issue; 7 respondents replied me in question form: maybe you didn’t exposed to bad odors?; and 4 promised to think over it to reply to me during our next meeting (their diplomatic refusal). After 6 months, for the same question, respondents add in their answer - a vaccination issue: they think that because of I have vaccinated against corona, I am not sick of influenza!

Since this work is public oriented, as a supplementary (to visualize) we add the above bar graph: in it the “I do not know, I don’t want to talk about such issue and will tell you next time, are indicate less awareness, sense of unsatisfactory-accusation-abused by regulators, etc. about which we will further interpret to responsible bodies.

4.1.2.2 Health workers interview’s result
We have had a possibility to interview 22 medical workers (from 3 medical centers, Addis Ababa health bureau and Ethiopian Health Ministry). As a result: 3 of them do not want to discuss with me; 9 were related it with immune system, 3 related it directly to hygiene, whereas 7 directly believe that the face mask is the reason why I have no flu during the pandemic

4.2          Clinic-epidemiology based secondary data on prevalence of RTIDs within the last 5-7 years
Data collection on: influenza, TB like RTIDs of 2015-2019 and the two pandemic years (2020-2021).

For this work not to make it bulky through listing 200 countries, we can just divide them into three categories: developed and developing, to holydays and production seasons, whereas, for geographical-climate issue, we can divide the globe into three: north, south hemispheres, and tropical regions. For this part the result of 4.2 mainly the graphs 2-5, can serve to determine the peak season for influenza like illness of the others RTID seasonal burden too. Additionally, in the CDC information [31]. This part of data will help us to decide – in which month and may be for how long is better to start the SaSP mandate throughout the whole globe at a time. Our data sources’ location were distributed as follows:
4.2.1 Tropical regions (Data that we collected within the tropical region Africa (Ethiopia- Kenya as tropicals),
4.2.2 North hemisphere (Canada, USA, UK) as northern hemisphere and in Asia (Malaysia and South Korea derivative of northern hemisphere)
4.2.3 Southern hemisphere South Africa, Australia, Argentina (as southern hemisphere)
4.2.1 Tropical regions
4.2.1.1 The secondary data on prevalence of RTID that we have collected from 3 Addis Ababa health centers; from the city’s health bureau and the data that we achieved from ministry of health may represent the country’s prevalence of influenza: Procedures, through which we passed for performing a secondary data collection from health centers - Having a supporting letter from our University, and then from Ethiopian Ministry of Health, we collected data from health services sights: health center; health bureau, and Ministry of health (refer to table 9).;

4.2.1.1 Secondary sample data that we retrieved from 3 health centers; Addis Ababa City’s Health Bureau (represents around 30 health sights); and Ministry of Health (4 scanned samples):

4.2.1.2 Data on influenza like RTID retrieved from Kenya
Authors [2] stated the following: The World Health Organization (WHO) estimates that acute lower respiratory infections account for 4 million deaths per year. The rates are even higher in developing countries. 
As seen in the graph {9], during six years of surveillance in Kenya, influenza was associated with nearly 10 percent of hospitalized SARI cases and one-sixth of outpatient ILI cases. Most influenza-associated SARI and ILI cases were in children

                               

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